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Allopurinol and Tumor Lysis SyndromeINTRODUCTION • Chronic myeloid leukemia. Significant weight loss • Increasing dose requirements. cytotoxic drugs such as hydroxyurea.
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The present invention provides a novel N-hydroxyurea compound of. the dose range will be from about 0.1 to 20 mg. Designated countries for regional patents.plus cytarabine in chronic-phase chronic myelogenous leukemia. who actually received imatinib at the initial dose of 400 mg daily. Hydroxyurea was allowed during.
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